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The Tuberin/mTOR Pathway Promotes Apoptosis of Tubular Epithelial Cells in Diabetes

Apoptosis contributes to the development of diabetic nephropathy, but the mechanism by which high glucose (HG) induces apoptosis is not fully understood. Because the tuberin/mTOR pathway can modulate apoptosis, we studied the role of this pathway in apoptosis in type I diabetes and in cultured proxi...

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Detalhes bibliográficos
Main Authors: Velagapudi, Chakradhar, Bhandari, Basant S., Abboud-Werner, Sherry, Simone, Simona, Abboud, Hanna E., Habib, Samy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029899/
https://ncbi.nlm.nih.gov/pubmed/21289215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040352
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