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Tuberin Inhibits Production of the Matrix Protein Fibronectin in Diabetes

Exposure of proximal tubular epithelial cells to high glucose contributes to the accumulation of tubulointerstitial and matrix proteins in diabetic nephropathy, but how this occurs is not well understood. We investigated the effect of the signaling molecule tuberin, which modulates the mammalian tar...

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書誌詳細
主要な著者: Habib, Samy L., Yadav, Mukesh, Tizani, Shaza, Bhandari, Basant, Valente, Anthony J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458468/
https://ncbi.nlm.nih.gov/pubmed/22904348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030285
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