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Tuberin Inhibits Production of the Matrix Protein Fibronectin in Diabetes

Exposure of proximal tubular epithelial cells to high glucose contributes to the accumulation of tubulointerstitial and matrix proteins in diabetic nephropathy, but how this occurs is not well understood. We investigated the effect of the signaling molecule tuberin, which modulates the mammalian tar...

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Sonraí Bibleagrafaíochta
Main Authors: Habib, Samy L., Yadav, Mukesh, Tizani, Shaza, Bhandari, Basant, Valente, Anthony J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458468/
https://ncbi.nlm.nih.gov/pubmed/22904348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030285
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