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Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex

Reactive oxygen species (ROS) are an important endogenous source of DNA damage and oxidative stress in all cell types. Deficiency in tuberin resulted in increased oxidative DNA damage in renal cells. In this study, the role of tuberin in the regulating of ROS and NADPH oxidases was investigated. For...

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Publicat a:Cancer Sci
Autors principals: Habib, Samy L., Abboud, Hanna E.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982584/
https://ncbi.nlm.nih.gov/pubmed/27278252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12984
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