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A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

Cellular immunity has an inherent high level of functional heterogeneity. Capturing the full spectrum of these functions requires analysis of large numbers of effector molecules from single cells. We report a microfluidic platform designed for highly multiplexed (more than ten proteins), reliable, s...

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Detalhes bibliográficos
Main Authors: Ma, Chao, Fan, Rong, Ahmad, Habib, Shi, Qihui, Comin-Anduix, Begonya, Chodon, Thinle, Koya, Richard C, Liu, Chao-Chao, Kwong, Gabriel A., Radu, Caius G., Ribas, Antoni, Heath, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681612/
https://ncbi.nlm.nih.gov/pubmed/21602800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2375
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