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Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: Utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment

The autophagic process, which can facilitate breast cancer resistance to endocrine, cytotoxic, and molecularly targeted agents, is mainly regulated at the post-translational level. Although recent studies have suggested a possible transcriptome regulation of the autophagic genes, little is known abo...

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Detalhes bibliográficos
Main Authors: Cufí, Sílvia, Vazquez-Martin, Alejandro, Oliveras-Ferraros, Cristina, Corominas-Faja, Bruna, Urruticoechea, Ander, Martin-Castillo, Begoña, Menendez, Javier A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681498/
https://ncbi.nlm.nih.gov/pubmed/23307622
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