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Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency
The antidiabetic drug metformin efficiently circumvents the dilemma that in reducing the tumourigenicity of stem cells, their essence, specifically their pluripotency, must also be sacrificed. Metformin prevents the occurrence or drastically reduces the size and weight of teratoma-like masses after...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3520055/ https://ncbi.nlm.nih.gov/pubmed/23236586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00964 |
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