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Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin)
The rate of inherent resistance to single-agent trastuzumab in HER2-overexpressing metastatic breast carcinomas is impressive at above 70%. Unfortunately, little is known regarding the distinctive genetic signatures that could predict trastuzumab refractoriness ab initio. The epithelial-to-mesenchym...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507497/ https://ncbi.nlm.nih.gov/pubmed/22992620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22225 |
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