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Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency

The antidiabetic drug metformin efficiently circumvents the dilemma that in reducing the tumourigenicity of stem cells, their essence, specifically their pluripotency, must also be sacrificed. Metformin prevents the occurrence or drastically reduces the size and weight of teratoma-like masses after...

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Detaylı Bibliyografya
Asıl Yazarlar: Vazquez-Martin, Alejandro, Cufi, Sílvia, Lopez-Bonet, Eugeni, Corominas-Faja, Bruna, Oliveras-Ferraros, Cristina, Martin-Castillo, Begoña, Menendez, Javier A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520055/
https://ncbi.nlm.nih.gov/pubmed/23236586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00964
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