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Autophagy Facilitates the Development of Breast Cancer Resistance to the Anti-HER2 Monoclonal Antibody Trastuzumab

Autophagy has been emerging as a novel cytoprotective mechanism to increase tumor cell survival under conditions of metabolic stress and hypoxia as well as to escape chemotherapy-induced cell death. To elucidate whether autophagy might also protect cancer cells from the growth inhibitory effects of...

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Detalhes bibliográficos
Main Authors: Vazquez-Martin, Alejandro, Oliveras-Ferraros, Cristina, Menendez, Javier A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708925/
https://ncbi.nlm.nih.gov/pubmed/19606230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006251
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