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Novel CLN1 mutation with atypical juvenile neuronal ceroid lipofuscinosis

We detected a novel CLN1 gene mutation (p.Arg151X, heterogenous) in a 12-year-old boy. Low level of palmitoyl protein thioesterase and granular inclusion pattern in lymphocytes were also consistent with infantile Neuronal ceroid lipofuscinosis (INCL). However, the clinical phenotype was that of atyp...

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Detalhes bibliográficos
Main Authors: Khan, Arif, Chieng, Kwong S., Baheerathan, Aravindhan, Hussain, Nahin, Gosalakkal, Jayprakash
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680897/
https://ncbi.nlm.nih.gov/pubmed/23772246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1817-1745.111424
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