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Novel CLN1 mutation with atypical juvenile neuronal ceroid lipofuscinosis

We detected a novel CLN1 gene mutation (p.Arg151X, heterogenous) in a 12-year-old boy. Low level of palmitoyl protein thioesterase and granular inclusion pattern in lymphocytes were also consistent with infantile Neuronal ceroid lipofuscinosis (INCL). However, the clinical phenotype was that of atyp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Khan, Arif, Chieng, Kwong S., Baheerathan, Aravindhan, Hussain, Nahin, Gosalakkal, Jayprakash
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Medknow Publications & Media Pvt Ltd 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680897/
https://ncbi.nlm.nih.gov/pubmed/23772246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1817-1745.111424
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