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The Role of Transporters in the Toxicity of Nucleoside and Nucleotide Analogs
INTRODUCTION: Two families of nucleoside analogs have been developed to treat viral infections and cancer, but these compounds can cause tissue and cell-specific toxicity related to their uptake and subcellular activity which are dictated by host enzymes and transporters. Cellular uptake of these co...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679903/ https://ncbi.nlm.nih.gov/pubmed/22509856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2012.680885 |
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