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The Role of Transporters in the Toxicity of Nucleoside and Nucleotide Analogs

INTRODUCTION: Two families of nucleoside analogs have been developed to treat viral infections and cancer, but these compounds can cause tissue and cell-specific toxicity related to their uptake and subcellular activity which are dictated by host enzymes and transporters. Cellular uptake of these co...

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Autors principals: Koczor, Christopher A, Torres, Rebecca A, Lewis, W
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679903/
https://ncbi.nlm.nih.gov/pubmed/22509856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2012.680885
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