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Absence of a Universal Mechanism of Mitochondrial Toxicity by Nucleoside Analogs
Nucleoside analogs are associated with various mitochondrial toxicities, and it is becoming increasingly difficult to accommodate these differences solely in the context of DNA polymerase gamma inhibition. Therefore, we examined the toxicities of zidovudine (AZT) (10 and 50 μM; 2.7 and 13.4 μg/ml),...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913246/ https://ncbi.nlm.nih.gov/pubmed/17470651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00039-07 |
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