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Role of CD47 and Signal Regulatory Protein Alpha (SIRPα) in Regulating the Clearance of Viable or Aged Blood Cells

SUMMARY: The ubiquitously expressed cell surface glycoprotein CD47 is expressed by virtually all cells in the host, where it can function to regulate integrin-mediated responses, or constitute an important part of the erythrocyte band 3/Rh multi-protein complex. In addition, CD47 can protect viable...

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Bibliographic Details
Main Author: Per-Arne, Oldenborg
Format: Artigo
Language:Inglês
Published: S. Karger GmbH 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678265/
https://ncbi.nlm.nih.gov/pubmed/23801922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342537
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