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Cd47-Signal Regulatory Protein α (Sirpα) Regulates Fcγ and Complement Receptor–Mediated Phagocytosis

In autoimmune hemolytic anemia (AIHA), circulating red blood cells (RBCs) opsonized with autoantibody are recognized by macrophage Fcγ and complement receptors. This triggers phagocytosis and elimination of RBCs from the circulation by splenic macrophages. We recently found that CD47 on unopsonized...

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Bibliografiska uppgifter
Huvudupphovsmän: Oldenborg, Per-Arne, Gresham, Hattie D., Lindberg, Frederik P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193364/
https://ncbi.nlm.nih.gov/pubmed/11283158
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