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Signal regulatory protein alpha (SIRPα) / CD47 interaction and function
SIRPα is an inhibitory receptor present on myeloid cells that interacts with a widely distributed membrane protein CD47. The activating member SIRPβ, despite extensive sequence similarity to SIRPα in the extracellular region, shows negligible binding to CD47. The SIRPα / CD47 interaction is unusual...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128989/ https://ncbi.nlm.nih.gov/pubmed/19223164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.01.008 |
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