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Selective mitochondrial Ca(2+) uptake deficit in disease endstage vulnerable motoneurons of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that targets some somatic motoneuron populations, while others, e.g. those of the oculomotor system, are spared. The pathophysiological basis of this pattern of differential vulnerability, which is preserved in a transgenic mou...

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Detalhes bibliográficos
Main Authors: Fuchs, Andrea, Kutterer, Sylvie, Mühling, Tobias, Duda, Johanna, Schütz, Burkhard, Liss, Birgit, Keller, Bernhard U, Roeper, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678052/
https://ncbi.nlm.nih.gov/pubmed/23401612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.247981
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