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Soma size and Ca(v)1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1(G93A) mouse model of ALS

Although the loss of motoneurons is an undisputed feature of amyotrophic lateral sclerosis (ALS) in man and in its animal models (SOD1 mutant mice), how the disease affects the size and excitability of motoneurons prior to their degeneration is not well understood. This study was designed to test th...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Shoenfeld, Liza, Westenbroek, Ruth E., Fisher, Erika, Quinlan, Katharina A., Tysseling, Vicki M., Powers, Randall K., Heckman, Charles J., Binder, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246589/
https://ncbi.nlm.nih.gov/pubmed/25107988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12113
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