Soma size and Ca(v)1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1(G93A) mouse model of ALS

Although the loss of motoneurons is an undisputed feature of amyotrophic lateral sclerosis (ALS) in man and in its animal models (SOD1 mutant mice), how the disease affects the size and excitability of motoneurons prior to their degeneration is not well understood. This study was designed to test th...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Shoenfeld, Liza, Westenbroek, Ruth E., Fisher, Erika, Quinlan, Katharina A., Tysseling, Vicki M., Powers, Randall K., Heckman, Charles J., Binder, Marc D.
Format: Artigo
Language:Inglês
Published: Wiley Periodicals, Inc. 2014
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246589/
https://ncbi.nlm.nih.gov/pubmed/25107988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12113
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