PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis()

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic peptide with autocrine neuroprotective and paracrine anti-inflammatory properties in various models of acute neuronal damage and neurodegenerative diseases. Therefore, we examined a possible beneficial role of endogenous PAC...

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Detalhes bibliográficos
Main Authors: Ringer, Cornelia, Büning, Luisa-Sybille, Schäfer, Martin K.H., Eiden, Lee E., Weihe, Eberhard, Schütz, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955759/
https://ncbi.nlm.nih.gov/pubmed/23466699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.02.010
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