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STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons
The neuroprotective actions of PACAP (pituitary adenylate cyclase-activating polypeptide) in vitro and in vivo suggest that activation of its cognate G protein-coupled receptor PAC1 or downstream signaling molecules, and thus activation of PACAP target genes, could be of therapeutic benefit. Here we...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256285/ https://ncbi.nlm.nih.gov/pubmed/21975601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-011-9653-9 |
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