The Oral Antidiabetic Pioglitazone Protects from Neurodegeneration and Amyotrophic Lateral Sclerosis-Like Symptoms in Superoxide Dismutase-G93A Transgenic Mice

Amyotrophic lateral sclerosis (ALS) represents a fatal neurodegenerative disorder characterized by progressive death of the upper and lower motor neurons. Because accompanying inflammation may interact with and promote neurodegeneration, anti-inflammatory treatment strategies are being evaluated. Be...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schütz, Burkhard, Reimann, Jens, Dumitrescu-Ozimek, Lucia, Kappes-Horn, Karin, Landreth, Gary E., Schürmann, Britta, Zimmer, Andreas, Heneka, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725264/
https://ncbi.nlm.nih.gov/pubmed/16120782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2038-05.2005
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