Immature Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Mutations in human copper-zinc superoxide dismutase (SOD1) cause an inherited form of amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease, motor neuron disease). Insoluble forms of mutant SOD1 accumulate in neural tissues of human ALS patients and in spinal cords of transgenic mice expressing t...

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Bibliografiske detaljer
Main Authors: Seetharaman, Sai V., Prudencio, Mercedes, Karch, Celeste, Holloway, Stephen P., Borchelt, David R., Hart, P. John
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850267/
https://ncbi.nlm.nih.gov/pubmed/19596823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0903-MR-104
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