Immature Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Mutations in human copper-zinc superoxide dismutase (SOD1) cause an inherited form of amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease, motor neuron disease). Insoluble forms of mutant SOD1 accumulate in neural tissues of human ALS patients and in spinal cords of transgenic mice expressing t...

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Detalhes bibliográficos
Main Authors: Seetharaman, Sai V., Prudencio, Mercedes, Karch, Celeste, Holloway, Stephen P., Borchelt, David R., Hart, P. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850267/
https://ncbi.nlm.nih.gov/pubmed/19596823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0903-MR-104
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