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Immature Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Mutations in human copper-zinc superoxide dismutase (SOD1) cause an inherited form of amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease, motor neuron disease). Insoluble forms of mutant SOD1 accumulate in neural tissues of human ALS patients and in spinal cords of transgenic mice expressing t...

詳細記述

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書誌詳細
主要な著者: Seetharaman, Sai V., Prudencio, Mercedes, Karch, Celeste, Holloway, Stephen P., Borchelt, David R., Hart, P. John
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850267/
https://ncbi.nlm.nih.gov/pubmed/19596823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0903-MR-104
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