Impaired Extracellular Secretion of Mutant Superoxide Dismutase 1 Associates with Neurotoxicity in Familial Amyotrophic Lateral Sclerosis

Mutations in the intracellular metalloenzyme superoxide dismutase 1 (SOD1) are linked to neurotoxicity in familial amyotrophic lateral sclerosis (ALS) by an unclear mechanism. Golgi fragmentation and endoplasmic reticulum stress are early hallmarks of spinal motor neuron pathology in transgenic mice...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Turner, Bradley J., Atkin, Julie D., Farg, Manal A., Zang, Da Wei, Rembach, Alan, Lopes, Elizabeth C., Patch, Justin D., Hill, Andrew F., Cheema, Surindar S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725218/
https://ncbi.nlm.nih.gov/pubmed/15634772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4253-04.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados