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Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells.

We isolated and characterized three spontaneous mutants of Chinese hamster ovary cells that were deficient in dihydrofolate reductase activity. All three mutants contained no detectable enzyme activity and produced dihydrofolate reductase mRNA species that were shorter than those of the wild type by...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Mitchell, P J, Urlaub, G, Chasin, L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.6.1926-1935.1986
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