Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells.
We isolated and characterized three spontaneous mutants of Chinese hamster ovary cells that were deficient in dihydrofolate reductase activity. All three mutants contained no detectable enzyme activity and produced dihydrofolate reductase mRNA species that were shorter than those of the wild type by...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.6.1926-1935.1986 |
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