Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition

Human LIN28A and LIN28B are RNA-binding proteins (RBPs) conserved in animals with important roles during development and stem cell reprogramming. We used Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP) in HEK293 cells and identified a largely overlapping set...

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Bibliographic Details
Main Authors: Hafner, Markus, Max, Klaas E.A., Bandaru, Pradeep, Morozov, Pavel, Gerstberger, Stefanie, Brown, Miguel, Molina, Henrik, Tuschl, Thomas
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677277/
https://ncbi.nlm.nih.gov/pubmed/23481595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036491.112
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