Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

microRNAs (miRNAs) regulate the expression of mRNAs in animals and plants through miRNA-containing ribonucleoprotein particles (RNPs). At the core of these miRNA silencing effector complexes are the Argonaute (AGO) proteins that bind miRNAs and mediate target mRNA recognition. We generated HEK293 ce...

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Main Authors: Landthaler, Markus, Gaidatzis, Dimos, Rothballer, Andrea, Chen, Po Yu, Soll, Steven Joseph, Dinic, Lana, Ojo, Tolulope, Hafner, Markus, Zavolan, Mihaela, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590962/
https://ncbi.nlm.nih.gov/pubmed/18978028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1351608
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