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Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C–miRNA complexes and the degradation of miRNA targets
How miRNAs recognize their target sites is a puzzle that many experimental and computational studies aimed to solve. Several features, such as perfect pairing of the miRNA seed, additional pairing in the 3′ region of the miRNA, relative position in the 3′ UTR, and the A/U content of the environment...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775596/ https://ncbi.nlm.nih.gov/pubmed/19767416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.091181.109 |
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