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Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

The brain tumor glioblastoma multiforme (GBM) is among the most lethal forms of human cancer. Here, we report that a small subset of GBMs (3.1%; 3 of 97 tumors examined) harbors oncogenic chromosomal translocations that fuse in-frame the tyrosine kinase coding domains of fibroblast growth factor rec...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Singh, Devendra, Chan, Joseph Minhow, Zoppoli, Pietro, Niola, Francesco, Sullivan, Ryan, Castano, Angelica, Liu, Eric Minwei, Reichel, Jonathan, Porrati, Paola, Pellegatta, Serena, Qiu, Kunlong, Gao, Zhibo, Ceccarelli, Michele, Riccardi, Riccardo, Brat, Daniel J., Guha, Abhijit, Aldape, Ken, Golfinos, John G., Zagzag, David, Mikkelsen, Tom, Finocchiaro, Gaetano, Lasorella, Anna, Rabadan, Raul, Iavarone, Antonio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677224/
https://ncbi.nlm.nih.gov/pubmed/22837387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1220834
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