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Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
Poly(ADP-ribose) polymerases (PARPs) are NAD(+) dependent enzymes that were identified as DNA repair proteins, however, today it seems clear that PARPs are responsible for a plethora of biological functions. Sirtuins (SIRTs) are NAD(+)-dependent deacetylase enzymes involved in the same biological pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676863/ https://ncbi.nlm.nih.gov/pubmed/23357756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2013.01.004 |
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