A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer

BRCA mutations are the main known hereditary factor for breast cancer. Notably, poly (ADP-ribose) polymerase 1 (PARP1) expression status plays a critical role in breast cancer progression and the clinical development of PARP1 inhibitors to treat BRCA-mutated breast cancer has advanced rapidly. Howev...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Main Authors: Li, Da, Bi, Fang-Fang, Chen, Na-Na, Cao, Ji-Min, Sun, Wu-Ping, Zhou, Yi-Ming, Li, Chun-Yan, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
Assuntos:
Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613991/
https://ncbi.nlm.nih.gov/pubmed/25485588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.956507
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