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Poly(ADP-ribose) Polymerase-1 Down-regulates BRCA2 Expression through the BRCA2 Promoter

Expression of the BRCA2 tumor suppressor gene is tightly linked to its roles in DNA damage repair and maintenance of chromosomal stability and genomic integrity. Three transcription factors that activate (USF, NF-κB, and Elf1) and a single factor that represses (SLUG) BRCA2 promoter activity have be...

詳細記述

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書誌詳細
主要な著者: Wang, Jinhua, Bian, Chunjing, Li, Jing, Couch, Fergus J., Wu, Kangjian, Zhao, Robert Chunhua
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605989/
https://ncbi.nlm.nih.gov/pubmed/18990703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803693200
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