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Poly(ADP-ribose) Polymerase-1 Down-regulates BRCA2 Expression through the BRCA2 Promoter

Expression of the BRCA2 tumor suppressor gene is tightly linked to its roles in DNA damage repair and maintenance of chromosomal stability and genomic integrity. Three transcription factors that activate (USF, NF-κB, and Elf1) and a single factor that represses (SLUG) BRCA2 promoter activity have be...

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Main Authors: Wang, Jinhua, Bian, Chunjing, Li, Jing, Couch, Fergus J., Wu, Kangjian, Zhao, Robert Chunhua
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605989/
https://ncbi.nlm.nih.gov/pubmed/18990703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803693200
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