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Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

Poly(ADP-ribose) polymerases (PARPs) are NAD(+) dependent enzymes that were identified as DNA repair proteins, however, today it seems clear that PARPs are responsible for a plethora of biological functions. Sirtuins (SIRTs) are NAD(+)-dependent deacetylase enzymes involved in the same biological pr...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Sauve, Anthony A., Bai, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676863/
https://ncbi.nlm.nih.gov/pubmed/23357756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2013.01.004
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