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Lack of influence of prion protein gene expression on kainate-induced seizures in mice: studies using congenic, coisogenic and transgenic strains

Prion protein (PrP) is a glycosylphosphatidylinositol (GPI) anchored cell surface protein expressed by many cells, including those of the mammalian nervous system. At present the physiologic functions of PrP remain unclear. Deletion of Prnp, the gene encoding PrP in mice, has been shown to alter nor...

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書誌詳細
主要な著者: Striebel, James F., Race, Brent, Pathmajeyan, Melissa, Rangel, Alejandra, Chesebro, Bruce
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676307/
https://ncbi.nlm.nih.gov/pubmed/23415788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.02.004
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