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Genetic control of D(H) reading frame and its effect on B cell development and antigen-specific antibody production
The power of the adaptive immune system to identify novel antigens depends on the ability of lymphocytes to create antigen receptors with diverse antigen-binding sites. For immunoglobulins, CDR-H3 lies at the center of the antigen binding site where it often plays a key role in antigen binding. It i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676173/ https://ncbi.nlm.nih.gov/pubmed/20666706 |
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