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Preimmune Control of the Variance of TCR CDR-B3: Insights Gained From Germline Replacement of a TCR Dβ Gene Segment With an Ig D(H) Gene Segment
We have previously shown that the sequence of the immunoglobulin diversity gene segment (D(H)) helps dictate the structure and composition of complementarity determining region 3 of the immunoglobulin heavy chain (CDR-H3). In order to test the role of germline D sequence on the diversity of the prei...
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| Udgivet i: | Front Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7518465/ https://ncbi.nlm.nih.gov/pubmed/33042119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02079 |
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