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Recirculating bone marrow B cells in C57BL/6 mice are more tolerant of highly hydrophobic and highly charged CDR-H3s than those in BALB/c mice

To test whether mechanisms controlling the range of diversity of the developing antibody repertoire in C57BL/6 mice (IgH(b)) operate similarly to those identified in BALB/c mice (IgH(a)), we compared the sequences of V(H)7183-containing H-chain transcripts from sorted adult bone marrow C57BL/6 B-cel...

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Bibliografiske detaljer
Main Authors: Khass, Mohamed, Buckley, Kevin, Kapoor, Pratibha, Schelonka, Robert L., Watkins, Leticia S., Zhuang, Yingxin, Schroeder, Harry W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653428/
https://ncbi.nlm.nih.gov/pubmed/23225217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242936
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