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Alterations in B cell development, CDR-H3 repertoire and dsDNA binding antibody production among C57BL/6 ΔD-iD mice congenic for the lupus susceptibility loci sle1, sle2, or sle3
Systemic lupus erythematosus is an autoimmune disease that reflects a failure to block production of self-reactive antibodies, especially those that bind double stranded DNA (dsDNA). Backcrossing the lupus-prone NZM2410 genome onto C57BL/6 led to the identification of three genomic intervals, termed...
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| Publicado no: | Autoimmunity |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551388/ https://ncbi.nlm.nih.gov/pubmed/28166678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08916934.2016.1272597 |
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