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Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production

All jawed vertebrates limit use of D(H) reading frames (RFs) that are enriched for hydrophobic amino acids. In BALB/c mice, DFL16.1 RF2 encodes valine and isoleucine. To test whether increased use of RF2 affects B cell function, we examined B cell development and antibody production in mice with an...

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Main Authors: Schelonka, Robert L., Zemlin, Michael, Kobayashi, Ryoki, Ippolito, Gregory C., Zhuang, Yingxin, Gartland, G. Larry, Szalai, Alex, Fujihashi, Kohtaro, Rajewsky, Klaus, Schroeder, Harry W.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679994/
https://ncbi.nlm.nih.gov/pubmed/19050258
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