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THE PERITONEAL CAVITY B-2 ANTIBODY REPERTOIRE APPEARS TO REFLECT MANY OF THE SAME SELECTIVE PRESSURES THAT SHAPE THE B-1a AND B-1b REPERTOIRES

To assess the extent and nature of somatic categorical selection of CDR-H3 content in peritoneal cavity (PerC) B cells, we analyzed the composition of V(H)7183DJCμ transcripts derived from sorted PerC B-1a, B-1b, and B-2 cells. We divided these sequences into those that contained N nucleotides (N+)...

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Библиографические подробности
Главные авторы: Vale, Andre M., Tanner, Jason M., Schelonka, Robert L., Zhuang, Yingxin, Zemlin, Michael, Gartland, G. Larry, Schroeder, Harry W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667605/
https://ncbi.nlm.nih.gov/pubmed/20956345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001423
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