Differences in the Composition of the Human Antibody Repertoire by B Cell Subsets in the Blood

The vast initial diversity of the antibody repertoire is generated centrally by means of a complex series of V(D)J gene rearrangement events, variation in the site of gene segment joining, and TdT catalyzed N-region addition. Although the diversity is great, close inspection has revealed distinct an...

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Detalhes bibliográficos
Principais autores: Mroczek, Eva Szymanska, Ippolito, Gregory C., Rogosch, Tobias, Hoi, Kam Hon, Hwangpo, Tracy A., Brand, Marsha G., Zhuang, Yingxin, Liu, Cun Ren, Schneider, David A., Zemlin, Michael, Brown, Elizabeth E., Georgiou, George, Schroeder, Harry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958703/
https://ncbi.nlm.nih.gov/pubmed/24678310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00096
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