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Systematic Characterization and Comparative Analysis of the Rabbit Immunoglobulin Repertoire

Rabbits have been used extensively as a model system for the elucidation of the mechanism of immunoglobulin diversification and for the production of antibodies. We employed Next Generation Sequencing to analyze Ig germline V and J gene usage, CDR3 length and amino acid composition, and gene convers...

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Autors principals: Lavinder, Jason J., Hoi, Kam Hon, Reddy, Sai T., Wine, Yariv, Georgiou, George
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076286/
https://ncbi.nlm.nih.gov/pubmed/24978027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101322
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