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Dynamics of heavy chain junctional length biases in antibody repertoires

Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...

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Pubblicato in:Commun Biol
Autori principali: Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://ncbi.nlm.nih.gov/pubmed/32358517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0931-3
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