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Dynamics of heavy chain junctional length biases in antibody repertoires

Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...

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Detalles Bibliográficos
Publicado en:Commun Biol
Main Authors: Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://ncbi.nlm.nih.gov/pubmed/32358517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0931-3
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