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Dynamics of heavy chain junctional length biases in antibody repertoires

Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...

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Bibliografiska uppgifter
I publikationen:Commun Biol
Huvudupphovsmän: Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://ncbi.nlm.nih.gov/pubmed/32358517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0931-3
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