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High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

Antibodies' protective, pathological, and therapeutic properties result from their considerable diversity. This diversity is almost limitless in potential, but actual diversity is still poorly understood. Here we use deep sequencing to characterize the diversity of the heavy-chain CDR3 region,...

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Hlavní autoři: Arnaout, Ramy, Lee, William, Cahill, Patrick, Honan, Tracey, Sparrow, Todd, Weiand, Michael, Nusbaum, Chad, Rajewsky, Klaus, Koralov, Sergei B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150326/
https://ncbi.nlm.nih.gov/pubmed/21829618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022365
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