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Dynamics of heavy chain junctional length biases in antibody repertoires

Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://ncbi.nlm.nih.gov/pubmed/32358517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0931-3
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