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Complete Protection against Severe Acute Respiratory Syndrome Coronavirus-Mediated Lethal Respiratory Disease in Aged Mice by Immunization with a Mouse-Adapted Virus Lacking E Protein

Zoonotic coronaviruses, including the one that caused severe acute respiratory syndrome (SARS), cause significant morbidity and mortality in humans. No specific therapy for any human coronavirus is available, making vaccine development critical for protection against these viruses. We previously sho...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fett, Craig, DeDiego, Marta L., Regla-Nava, Jose A., Enjuanes, Luis, Perlman, Stanley
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676143/
https://ncbi.nlm.nih.gov/pubmed/23576515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00087-13
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