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Complete Protection against Severe Acute Respiratory Syndrome Coronavirus-Mediated Lethal Respiratory Disease in Aged Mice by Immunization with a Mouse-Adapted Virus Lacking E Protein

Zoonotic coronaviruses, including the one that caused severe acute respiratory syndrome (SARS), cause significant morbidity and mortality in humans. No specific therapy for any human coronavirus is available, making vaccine development critical for protection against these viruses. We previously sho...

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Bibliografische gegevens
Hoofdauteurs: Fett, Craig, DeDiego, Marta L., Regla-Nava, Jose A., Enjuanes, Luis, Perlman, Stanley
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676143/
https://ncbi.nlm.nih.gov/pubmed/23576515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00087-13
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