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Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

Current influenza virus vaccine strategies stimulate immune responses toward the globular head domain of the hemagglutinin protein in order to inhibit key steps of the virus life cycle. Because this domain is highly variable across strains, new vaccine formulations are required in most years. Here w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krammer, Florian, Pica, Natalie, Hai, Rong, Margine, Irina, Palese, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676110/
https://ncbi.nlm.nih.gov/pubmed/23576508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00641-13
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