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Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

Current influenza virus vaccine strategies stimulate immune responses toward the globular head domain of the hemagglutinin protein in order to inhibit key steps of the virus life cycle. Because this domain is highly variable across strains, new vaccine formulations are required in most years. Here w...

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Autores principales: Krammer, Florian, Pica, Natalie, Hai, Rong, Margine, Irina, Palese, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676110/
https://ncbi.nlm.nih.gov/pubmed/23576508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00641-13
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