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Mycobacterium tuberculosis Maltosyltransferase GlgE, a Genetically Validated Antituberculosis Target, Is Negatively Regulated by Ser/Thr Phosphorylation

GlgE is a maltosyltransferase involved in the biosynthesis of α-glucans that has been genetically validated as a potential therapeutic target against Mycobacterium tuberculosis. Despite also making α-glucan, the GlgC/GlgA glycogen pathway is distinct and allosterically regulated. We have used a comb...

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Bibliografiset tiedot
Päätekijät: Leiba, Jade, Syson, Karl, Baronian, Grégory, Zanella-Cléon, Isabelle, Kalscheuer, Rainer, Kremer, Laurent, Bornemann, Stephen, Molle, Virginie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675590/
https://ncbi.nlm.nih.gov/pubmed/23609448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398503
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